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当孕妇首次检测出有弓形虫抗体时,迫切需要解答“胎儿有无危险?”问题的关键是应弄清孕妇感染弓形虫的时间.仅凭临床症状远远不够,因弓形虫感染初期多无任何症状,但IgM抗体的升高是感染早期的特征,故用检测孕妇的IgM抗体判定感染时间具有重要意义.Remington及Miller1966年曾应用间接免疫荧光试验(IIFT),证明感染弓形虫一周内便呈强阳性,但也有阴性者,故不甚理想,近年来创用有特异性和敏感性的免疫吸附凝集试验(ISAGA),兼有直接凝集试验和双夹心酶联免疫吸附试验的优点.
When pregnant women first detected Toxoplasma antibodies, there is an urgent need to answer The key to the problem is to understand the timing of pregnant women infected with Toxoplasma gondii alone clinical symptoms are not enough, due to early stages of Toxoplasma infection More without any symptoms, but elevated IgM antibodies is characterized by early infection, so the detection of pregnant women with IgM antibodies to determine the time of infection is of great significance.Remington and Miller1966 years with the use of isofluorescent test (IIFT), that a week of infection with Toxoplasma gondii There was a strong positive, but also negative, it is not ideal, in recent years to create a specific and sensitive immunoadsorption agglutination test (ISAGA), both direct agglutination test and double-sandwich enzyme-linked immunosorbent assay .