滋养层制剂治疗原因不明的习惯性流产

来源 :国外医学.妇产科学分册 | 被引量 : 0次 | 上传用户:hjkl123lkjh
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习惯性流产较常见,病因也较多,对原因不明的习惯性流产目前已从免疫学及免疫遗传学角度加以注意,正常妊娠母体胎儿接触面出现的胎儿抗原可有效增强或诱发母体细胞的和激素的免疫调节机制,以保护胎儿不被排斥。但是这种保护作用有限,某些习惯性流产的妇女这种母体的免疫识别有所减弱。现在用外周血白细胞行主动同种免疫,可有益于这些病人以后的生育。此法简单,却有局限性,因母亲对人白细胞抗原(HLA)、红细胞或血小扳抗原有致敏的危险,也有发生围产期宿主对抗胎儿的疾患以及与输注有关的危险,如病毒传染等。而且用此法治疗后的妊娠有过严重宫内生长迟缓及胎儿先天性异常的报告。另外此法需筛选大量的供血 Habitual abortion is more common and causes more habitual abortion for unknown causes has been noted from the immunological and immunological genetic point of view, normal pregnancy maternal fetus fetal antigen appears to be able to enhance or induce maternal cells and Hormone immune regulation mechanism to protect the fetus is not excluded. However, this protective effect is limited, and the immunocompetence of such mothers is reduced in some habitual abortions. Active peripheral blood leukocyte line immunization now, can be beneficial to these patients after childbirth. This method is simple and has limitations because of the risk of mother being sensitized to human leukocyte antigen (HLA), erythrocyte or clarinet antigen, and also to the perinatal host’s disease in the fetus and the risks associated with infusion, such as the virus Infection and so on. And with this method after treatment of pregnancy has had severe intrauterine growth retardation and fetal congenital abnormalities report. In addition this method need to screen a large number of blood supply
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