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[目的]研究颞部星形胶质细胞瘤扩大切除方法的疗效。[方法]回顾性分析43例采取扩大切除术(实验组)和38例未采取扩大切除术(对照组)治疗的颞部星形胶质细胞瘤患者的临床资料。对比分析不同病理分级下不同手术方法的疗效差异。[结果]Ⅰ、Ⅱ级星形胶质细胞瘤患者中,实验组的术后并发症发生率(31.03%)高于对照组(8.00%),而KPS评分(70±10)低于对照组(80±10),但是实验组的复发率(17.24%)及中位生存期(55.3月)与对照组无明显差异。而Ⅲ、Ⅳ级胶质瘤患者中,实验组的术后并发症发生率与对照组无明显差异,实验组的复发率(7.14%)低于对照组(46.15%),且KPS评分(80±10)高于对照组(70±10)。实验组的中位生存期(34.7月)高于对照组(27.8月)。[结论]对于Ⅰ、Ⅱ级星形胶质细胞瘤,更积极的手术切除范围无临床意义,而对于Ⅲ、Ⅳ级星形胶质瘤患者,采取扩大切除术有利于提高患者的生存质量,降低复发率,并且延长患者的生存时间。
[Objective] To study the curative effect of enlarged resection of temporal astrocytoma. [Methods] The clinical data of 43 patients with temporal astrocytoma treated with extended resection (experimental group) and 38 patients without enlarged resection (control group) were retrospectively analyzed. The differences of curative effect between different surgical methods under different pathological grades were compared and analyzed. [Results] The incidence of postoperative complications (31.03%) in the experimental group was higher than that in the control group (8.00%), while the KPS score (70 ± 10) was lower in the patients with grade Ⅰ and Ⅱ astrocytoma (80 ± 10), but the recurrence rate (17.24%) and median survival time (55.3 months) in the experimental group had no significant difference with the control group. The incidence of postoperative complications in the experimental group was not significantly different from that in the control group. The recurrence rate (7.14%) in the experimental group was lower than that in the control group (46.15%), and the KPS score ± 10) higher than the control group (70 ± 10). The median survival time in the experimental group (34.7 months) was higher than that in the control group (27.8 months). [Conclusion] For the grade Ⅰ and grade Ⅱ astrocytomas, the more active resection range has no clinical significance. However, for patients with stage Ⅲ and Ⅳ astrocytoma, it is beneficial to improve the quality of life of the patients with enlarged resection, Reduce the recurrence rate, and extend the patient’s survival time.