论文部分内容阅读
目的:探讨充血性心力衰竭(CHF)患者甲状腺激素(TH)变化和心功能的关系。方法:用放射免疫法分别测定CHF患者36例(CHF组)和健康对照组23例(对照组)血清三碘甲状腺原氨酸(T3)、四碘甲状腺原氨酸(T4)、反三碘甲状腺原氨酸(rT3)及促甲状腺素(TSH),用超声心动图测定心排血量(CO)、左室射血分数(LVEF)、左室舒张末容积(LVEDV)、左室收缩末容积(LVESV)。结果:CHF组T3水平和LVEF、CO明显低于对照组,rT3和LVEDV、LVESV显著升高,且随着心力衰竭程度加重,其变化越明显。结论:TH变化对CHF患者心功能损害程度、治疗及预后具有重要意义。
Objective: To investigate the relationship between thyroid hormone (TH) and cardiac function in patients with congestive heart failure (CHF). Methods: The levels of serum triiodothyronine (T3), tetraiodothyronine (T4), anti-triiodine in 36 CHF patients (CHF group) and 23 healthy controls (control group) were determined by radioimmunoassay Thyroxine (THT) and thyrotropin (TSH) were measured. The cardiac output (CO), left ventricular ejection fraction (LVEF), left ventricular end diastolic volume (LVEDV) Volume (LVESV). Results: The levels of T3, LVEF and CO in CHF group were significantly lower than those in control group, while the levels of rT3, LVEDV and LVESV were significantly increased. The more obvious the changes were with the severity of heart failure. Conclusion: The change of TH is of great significance for the degree of cardiac dysfunction, treatment and prognosis in CHF patients.