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1971年 Burnet 首先提出免疫监视学说,即机体免疫系统中的免疫活性细胞包括 T 细胞、NK 细胞、巨噬细胞等能识别和破坏肿瘤细胞,发挥免疫监视作用.而肿瘤细胞逃避机体免疫系统的监视,无限制地生长下去的现象则被称之为免疫逃逸.
In 1971, Burnet first proposed the immunosurveillance theory that immune cells in the immune system of the body, including T cells, NK cells, and macrophages, can recognize and destroy tumor cells and exert immune surveillance. The tumor cells escape the surveillance of the immune system. The phenomenon of unlimited growth is called immune escape.