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乙酰唑胺(Diamox)和甲醋唑胺(Neptazane)为碳酸酐酶抑制剂,常用于青光眼降低眼压,以及癫痫发作和心脏疾病的治疗。虽然乙酰唑胺和有关的碳酸酐酶抑制剂可有许多不良的反应,最严重的是再生障碍性贫血。本文报告使用甲醋唑胺引起的二例再生障碍性贫血和一例粒细胞缺乏症。病例报告例一:76岁,女,1973年开始治疗左眼青光眼。右眼眼内压20mmHg,左眼35mmHg,双眼前房角开放,开始用2%毛果芸香硷和2%盐酸肾上腺素治疗。尽管使用溴化德美卡灵(Demecarium bromide),左眼眼内压仍然难予控制。为了努力控制眼内压,从1976年10
Diamox and Neptazane are carbonic anhydrase inhibitors commonly used to lower IOP in glaucoma and to treat seizures and heart disease. Although acetazolamide and related carbonic anhydrase inhibitors can have many adverse reactions, the most serious is aplastic anemia. This article reports the use of metconazole-induced two cases of aplastic anemia and one case of agranulocytosis. Case Report Case 1: 76 years old, female, 1973 left glaucoma treatment. Right eye intraocular pressure 20mmHg, left eye 35mmHg, eyes open anterior chamber angle, began with 2% pilocarpine and 2% epinephrine hydrochloride treatment. Despite the use of Demecarium bromide, intraocular pressure in the left eye remains difficult to control. In an effort to control intraocular pressure, from 1976 10