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mueller矩阵偏振成像可用于获取生物组织的浅表层生理学信息,在疾病早期诊断与预防中具有重要意义。而在偏振成像系统中直接使用商用面阵CMOS相机不能得到用于解算mueller矩阵的正确图像信息,限制了其在小型化内窥领域上的应用。对商用面阵CMOS的研究表明其光信号输入输出呈非线性映射关系。综合考虑到传感器固有的成像噪声,提出一种基于校正的方法对CMOS的输出数据进行映射以获取正确的组织偏振信息值。实验结果表明校正后的偏振信息可以解算得到正确的mueller矩阵值,误差可以控制在3%以内,对蚕丝样品的测试也证明了该方法的有效性。上述结果使得内窥探头上应用小型化的商用面阵CMOS图像传感器进行体内生物组织mueller矩阵测量成为可能。
Mueller matrix polarization imaging can be used to obtain biological tissue of the superficial layer of physiological information, in the early diagnosis and prevention of disease is of great significance. However, the direct use of commercial area array CMOS camera in the polarization imaging system can not obtain the correct image information for solving the mueller matrix, which limits its application in the field of miniaturized endoscopy. The research on commercial area array CMOS shows that the optical signal input and output are non-linearly mapped. Considering the inherent imaging noise of the sensor, a correction-based method is proposed to map the CMOS output data to obtain the correct value of the tissue polarization information. The experimental results show that the corrected polarization information can be used to calculate the correct mueller matrix value and the error can be controlled within 3%. The testing of silk samples also proves the effectiveness of the method. The above results make it possible to use the miniaturized commercial area array CMOS image sensor on the endoscopic probe for in vivo tissue mueller matrix measurement.