传统的抗心律失常药物疗效较好,但具有致心律失常、器官毒性等副作用.新上市的维纳卡兰是一种新型抗心律失常药物,为选择性心房钠/钾离子通道阻滞剂,研究表明在新近发作的心房颤动急性转复方面的疗效优于胺碘酮,且临床应用前景较好,对其合成路线进行综述. Traditional anti-arrhythmic drugs have a good curative effect, but have side effects such as arrhythmia, organ toxicity, etc. The newly listed Vincarnin is a new type of anti-arrhythmic drug, which is a selective atrial sodium / potassium channel blocker, Studies have shown that in the recent onset of acute atrial fibrillation recovery is superior to amiodarone, and the clinical application of good prospects for the synthesis of its review.