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目的研究复发性单纯疱疹性角膜炎（ｈｅｒｐｅｓｓｉｍｐｌｅｘｋｅｒａｔｉｔｉｓ，ＨＳＫ）患者外周血Ｔ－淋巴细胞亚群变化与血清可溶性白细胞介素－２受体（ｓｏｌｕｂｌｅｉｎｔｅｒｌｅｕｋｉｎ－２ｒｅｃｅｐｔｏｒ，ＳＩＬ－２Ｒ）水平的关系。方法测定了３０例复发性ＨＳＫ患者外周血Ｔ－淋巴细胞亚群，同时检测血清ＳＩＬ－２Ｒ的水平并与２５例健康人做对照。结果复发性单纯疱疹性角膜炎患者ＣＤ３、ＣＤ４／ＣＤ８均值与正常对照组相比明显降低；血清ＳＩＬ－２Ｒ与对照组比较显著增高。结论复发性ＨＳＫ患者体内免疫功能低下，ＳＩＬ－２Ｒ水平升高可能是其原因之一，这也为免疫治疗提供了一定依据。
Objective To study the relationship between the changes of T-lymphocyte subsets in peripheral blood and serum soluble interleukin-2 receptor (SIL-2R) levels in patients with recurrent herpessimplexkeratitis (HSK). Methods T-lymphocyte subsets in peripheral blood of 30 patients with recurrent HSK were measured. The level of serum SIL-2R was measured and compared with 25 healthy controls. Results The mean of CD3 and CD4 / CD8 in patients with recurrent herpes simplex keratitis was significantly lower than that in the control group. The serum SIL-2R level was significantly higher than that in the control group. Conclusion The immunosuppression and SIL-2R level in patients with recurrent HSK may be one of the reasons for this. This may provide a basis for immunotherapy.