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目的探讨孕妇生殖道B族链球菌(GBS)感染对母婴预后的影响,为临床诊疗提供参考依据。方法 261例孕妇,均给予阴道肛门分泌物GBS培养,记录所有孕妇生殖道GBS感染发生情况。根据感染情况,将261例孕妇分为阳性组(25例)和阴性组(236例),比较两组孕妇母婴预后情况。结果 GBS感染阳性组早产发生率为24.00%、新生儿感染发生率为16.00%、胎儿窘迫发生率为20.00%、胎膜早破发生率为16.00%、宫内感染发生率为20.00%,均显著高于GBS感染阴性组的4.66%、5.08%、3.81%、3.39%、5.08%,差异均具有统计学意义(P<0.05);两组新生儿窒息、新生儿黄疸、产后出血及产褥感染发生率比较差异无统计学意义(P>0.05)。结论孕妇生殖道B族链球菌感染会对其妊娠结局产生不良影响,同时,对胎儿出生之后也会产生一定影响;在临床诊疗过程中,应进一步加强孕妇GBS感染相关防控手段,以保证良好妊娠结局。
Objective To investigate the influence of genital B streptococcal (GBS) infection on the prognosis of maternal and infant in pregnant women and to provide a reference for clinical diagnosis and treatment. Methods A total of 261 pregnant women were given GBS culture of vaginal anal secretions. The incidence of GBS infection in the reproductive tract of all pregnant women was recorded. According to the infection, 261 pregnant women were divided into positive group (25 cases) and negative group (236 cases). The prognosis of pregnant women in both groups were compared. Results The prevalence of preterm birth was 24.00% in GBS positive group, 16.00% in neonatal infection, 20.00% in fetal distress, 16.00% in premature rupture of membranes, and 20.00% in intrauterine infection, both of which were significant (4.66%, 5.08%, 3.81%, 3.39%, 5.08% respectively) in the group with negative GBS infection, the difference was statistically significant (P <0.05). Neonatal asphyxia, neonatal jaundice, postpartum hemorrhage and puerperal infection The incidence was no significant difference (P> 0.05). Conclusions Infection of genital B streptococci in pregnant women will have an adverse effect on their pregnancy outcome, meanwhile it will also have an impact on the fetus after birth. In the clinical diagnosis and treatment, the prevention and control measures of GBS infection in pregnant women should be further strengthened to ensure good Pregnancy outcome.