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头孢曲松是第3代头孢菌素,具有广谱抗菌作用。该药易与胆汁和尿液中的钙离子结合,成为头孢曲松钙盐沉淀物,进而形成假性结石。多数头孢曲松相关假性结石患者无临床症状,超声检查是该病诊断的最常用方法,询问病史及用药情况有助于确诊。用药剂量、疗程、静脉滴注速度及禁食与脱水状态是头孢曲松相关假性结石发生的主要影响因素。假性结石具有可逆性,停药后可自行消失,无需手术。必要时应予对症治疗。
Ceftriaxone is the third generation cephalosporin, with broad-spectrum antibacterial effect. The drug easily with bile and urine calcium ions, as ceftriaxone calcium salt precipitate, and then the formation of pseudo-stone. Most ceftriaxone patients with pseudo-stone without clinical symptoms, ultrasound is the most commonly used method of diagnosis of the disease, ask history and medication to help confirm the diagnosis. Dose of medication, duration of treatment, intravenous infusion rate and fasting and dehydration are the main influencing factors of ceftriaxone related pseudo-stone. Pseudolithiasis reversible, after stopping can disappear on their own, without surgery. When necessary, should be symptomatic treatment.