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目的:探析二甲双胍+地特胰岛素治疗糖尿病肾病的临床疗效。方法:2016年1月-2017年1月,我院共收治糖尿病肾病患者136例,依照其入院单双次序将其分为对照组(n=68)与观察组(n=68)。对照组行地特胰岛素治疗,观察组在其基础上增加二甲双胍治疗。对两组患者临床治疗效果进行对比。结果:由本次研究可知,两组患者在治疗前,其FBG、2hPBG、HbA1c、24hMA1b水平并无显著差异(P>0.05),在治疗后均有明显改善,且观察组在改善幅度上优于对照组,其差异具有统计学意义(P<0.05)。结论:二甲双胍+地特胰岛素治疗糖尿病肾病具有较为显著的临床效果,可在临床治疗中大力推广。
Objective: To investigate the clinical efficacy of metformin plus detemir in the treatment of diabetic nephropathy. Methods: From January 2016 to January 2017, 136 patients with diabetic nephropathy were admitted to our hospital. Patients were divided into control group (n = 68) and observation group (n = 68). In the control group, insulin was administered to the observation group. Metformin was added to the observation group. The clinical effect of two groups of patients were compared. Results: According to this study, there was no significant difference in FBG, 2hPBG, HbA1c and 24hMA1b levels between the two groups before treatment (P> 0.05), and both groups were significantly improved after treatment, and the improvement rate in the observation group was excellent In the control group, the difference was statistically significant (P <0.05). Conclusion: Metformin plus detemir treatment of diabetic nephropathy has a significant clinical effect, which can be vigorously promoted in clinical treatment.