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目的:研究营养干预辅助硝苯地平控释片、酚妥拉明和硫酸镁药物三联法用于妊娠高血压对母婴结局的影响。方法:选择220例前来我院接受治疗的患有妊娠高血压的孕妇,平均分为研究组和对照组,每组各110例,研究组采用营养干预辅助硝苯地平控释片、酚妥拉明和硫酸镁药物三联疗法治疗,对照组采用营养干预辅助硫酸镁进行治疗,治疗结束后观察两组患者的疗效。结果:研究组患者治疗后收缩压和舒张压都显著低于对照组患者(P<0.05),自然分娩率显著高于对照组(P<0.05),剖宫产率显著低于对照组(P<0.05),产后出血、胎盘早剥、新生儿窒息、新生儿死亡率均显著优于对照组患者(P<0.05),不良反应发生率为15.45%,显著低于对照组43.64%(P<0.05)。结论:营养干预辅助硝苯地平控释片、酚妥拉明和硫酸镁药物三联疗法在血压变化、产妇分娩方式、妊娠结局及不良反应方面均显著优于营养干预辅助硫酸镁组,适合临床上广泛推广应用。
OBJECTIVE: To study the effects of nifedipine controlled-release tablets of nutritional intervention and triple therapy of phentolamine and magnesium sulfate on the outcome of pregnancy-induced hypertension in pregnant women. Methods: A total of 220 pregnant women with gestational hypertension who were treated in our hospital were selected and divided equally into study group and control group, with 110 cases in each group. The study group was treated with nifedipine controlled-release tablets Lamine and magnesium sulfate triple therapy therapy, the control group with nutritional intervention assisted magnesium sulfate treatment, the treatment was observed after the two groups of patients. Results: The systolic blood pressure and diastolic blood pressure in study group were significantly lower than those in control group (P <0.05), and the rate of natural childbirth was significantly higher than that of control group (P <0.05). The cesarean section rate was significantly lower than that of control group (P <0.05). The incidence of postpartum hemorrhage, placental abruption, neonatal asphyxia and neonatal mortality were significantly higher than those in the control group (P <0.05). The incidence of adverse reactions was 15.45%, significantly lower than that of the control group (43.64%, P < 0.05). Conclusion: Nifedipine controlled-release tablets and triple-therapy of phentolamine and magnesium sulfate are significantly better than nutritional intervention in magnesium sulfate group in terms of blood pressure changes, maternal delivery, pregnancy outcomes and adverse reactions, which is suitable for clinical application Promote the application.