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目的:探讨内镜下金属钛夹联合医用生物纤维蛋白胶对Dieulafoy病上消化道出血的止血效果。方法:经内镜检查诊断Dieulafoy病上消化道出血患者18例,于内镜下应用Olympus金属钛夹直接夹闭出血病灶,并喷洒医用生物纤维蛋白胶止血。观察即时止血率、再出血率。结果:均一次止血成功,即时止血率100%。1例于治疗后2 d再次出血,再行金属钛夹及医用生物纤维蛋白胶止血,效果不满意,转外科手术治疗,余17例术后随访1 a均未再次出血。结论:内镜下金属钛夹联合医用生物纤维蛋白胶治疗Dieulafoy病上消化道出血疗效满意。
Objective: To investigate the effect of endoscopic titanium clip combined with medical fibrin glue on the hemostasis of upper gastrointestinal bleeding in Dieulafoy’s disease. Methods: Eighteen patients diagnosed as Dieulafoy’s upper gastrointestinal bleeding by endoscopy were clinically treated with Olympus Titanium Clip to directly hemostat the hemorrhage and spray medical fibrin glue. Observed immediate hemostasis, rebleeding rate. Results: Hemostasis was successful once and immediate hemostasis rate was 100%. One patient was hemorrhaged again 2 days after treatment, and then hemodialysis was performed with metal titanium clips and medical fibrin glue. The results were unsatisfactory and were surgically treated. All the remaining 17 cases did not hemorrhage after 1 year follow-up. Conclusion: Endoscopic titanium clip combined with medical fibrin glue in the treatment of upper gastrointestinal bleeding Dieulafoy disease with satisfactory results.