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大剂量丹参静滴对食管癌放疗增敏作用的前瞻性研究，采用随机开放式平行设计，分为综合组（丹参十放疗）和单放组（单纯放疗）。临床观察表明，综合组疗效比单放组提高12．7％，差异有显著性，P＜0．05；两组在治疗过程中对白细胞（WBC）的影响，综合组影响较轻或较少影响，单放组影响较多较重，两组比较差异有显著性，P＜t0.05；两组治疗结束后对外周血淋巴细胞rDNA转录活性分析显示，综合组明显优于单放组，差异非常有显著性，P＜t0．01；对放射性食管炎发生程度，两组相差无显著性，P＞0．05。由此表明，应用丹参辅助放疗治疗食管癌可达到提高近期疗效，增强机体免疫机能，刺激骨髓造血，辅助升白细胞效果，确保治疗顺利进行。
The prospective study of high-dose Salvia miltiorrhiza intravenous injection for sensitization of esophageal cancer radiotherapy used a random open parallel design and was divided into a comprehensive group (Salvia ten radiotherapy) and a radiotherapy group (radiotherapy alone). Clinical observations showed that the efficacy of the integrated group was 12.7% higher than that of the radiotherapy group, and the difference was significant (P<0.05); the effect of the two groups on white blood cells (WBC) during the treatment process was milder or less affected in the integrated group. The effects of the single-release group were more severe and heavier, with significant difference between the two groups (P<0.05). Analysis of the rDNA transcription activity of peripheral blood lymphocytes after treatment in the two groups showed that the integrated group was significantly better than the single-release group. The difference was very significant, P0.05. This shows that the application of Salvia miltiorrhea adjuvant radiotherapy for the treatment of esophageal cancer can improve the short-term efficacy, enhance the body’s immune function, stimulate the bone marrow hematopoietic, help to promote the effect of white blood cells, to ensure the smooth progress of treatment.