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包虫病是世界范围流行的一种人畜共患的寄生虫病,迄今在治疗上尚无理想的化疗药物。1977年以来,许多国内外学者用甲苯咪唑(MBZ)、吡喹酮(PQT)等药物对包虫病进行试验治疗,各家效果不一,其共同缺点是药物难溶于水。1983年 Saimot 等用丙硫咪唑(ABZ)对11例包虫病人作了试验治疗,该药最大优点吸收良好。我院从1985年5月至1989年1月用 ABZ与消包丸合治多发性包虫病154例,ABZ 单独治疗多发性包虫病19例,其中对29例行内囊摘除术采集内囊和原头蚴,用病理组织学、透射电镜、扫描电镜观察超微结构改变,报告如下:
Echinococcosis is a zoonotic parasitic disease prevalent in the world, so far there is no ideal chemotherapy drug in the treatment. Since 1977, many domestic and foreign scholars have tried different treatments with echinococcosis, such as MBZ and PQT. The common weakness is that they are poorly soluble in water. In 1983, Saimot and other albendazole (ABZ) on the 11 cases of hydatid disease trial, the drug’s biggest advantages of good absorption. In our hospital from May 1985 to January 1989 with ABZ and Xiao Bao Pill combined treatment of multiple echinococcosis in 154 cases, ABZ treatment of multiple echinococcosis in 19 cases, of which 29 cases of internal capsule enucleation acquisition of internal capsule And the original cercariae, with histopathology, transmission electron microscopy, scanning electron microscopy ultrastructural changes, the report is as follows: