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目的探讨妊娠梅毒的流行特征、妊娠结局和围产儿预后。方法根据妊娠期是否抗梅毒治疗,将126例经血清学检查确诊为梅毒的孕妇分为两组:孕期治疗组59例,妊娠前治疗组67例,比较两组孕妇的妊娠结局及围产儿预后。结果①妊娠结局:妊娠前治疗组明显好于孕期治疗组,两组比较,有极显著性差异。②围产儿预后:妊娠前治疗组孕妇分娩正常新生儿的例教明显多于孕期治疗组,且分娩先天梅毒儿、窒息儿、低体重儿、畸形儿发生率及围生儿死亡率明显少于未治疗组,两组比较差异有极显著性(p<0.01)。结论孕早期进行常规梅毒筛查尤为重要;妊娠前正规治疗后的梅毒患者所生的胎儿预后较好;妊娠期梅毒患者及早行抗梅毒治疗能有效地改善妊娠结局和围产儿预后。
Objective To investigate the prevalence of syphilis in pregnancy, the outcome of pregnancy and the prognosis of perinatal. Methods According to whether anti-syphilis treatment during pregnancy, 126 cases of pregnant women diagnosed with syphilis by serological test were divided into two groups: 59 cases of pregnancy treatment group, 67 cases of pre-pregnancy treatment group, comparing the pregnancy outcome and the prognosis of perinatal . Results ① pregnancy outcome: pre-pregnancy treatment group was significantly better than the pregnancy treatment group, the two groups, there was a very significant difference. ② Perinatal Prognosis: Pre-pregnancy treatment group of pregnant women giving birth normal newborns were significantly more cases than pregnant treatment group, and childbirth congenital syphilis, suffocation, low birth weight infants, deformed children and perinatal mortality was significantly less than The untreated group, the difference between the two groups was significant (p <0.01). Conclusions Pregnancy syphilis screening in the first trimester is particularly important; pre-pregnancy syphilis patients after regular treatment of fetuses born better prognosis; syphilis in patients with gestational anti-syphilis early treatment can effectively improve the outcome of pregnancy and perinatal prognosis.