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目的探讨心肌肌钙蛋白T(cTnT)对小儿急性病毒性心肌炎的诊断意义。方法对102例疑似小儿急性病毒性心肌炎患儿分别于入院时即发病(4.5±3.8)d,抽取周围静脉血同时测定cTnT和CK-MB水平,观察小儿急性病毒性心肌炎这两项指标的阳性率。结果 cTnT和CK-MB在小儿急性病毒性心肌炎患儿就诊时的阳性率分别为94.3%、95.5%。两组间的差异无统计学意义(P>0.05)。cTnT检测急性病毒性心肌炎的特异性(92.2%)优于CK-MB(71.4%),其敏感性(94.3%)低于CK-MB(95.5%)。结论在诊断小儿急性病毒性心肌炎时,cTnT检测方便、快速,特异性高,对小儿急性病毒性心肌炎的诊断具有很好的价值,联合检测cTnT及CK-MB,可提高诊断率,减少漏诊率。
Objective To investigate the diagnostic value of cardiac troponin T (cTnT) in children with acute viral myocarditis. Methods A total of 102 children with suspected viral myocarditis were admitted to hospital at the time of admission (4.5 ± 3.8 days) respectively. Peripheral venous blood samples were taken for simultaneous determination of cTnT and CK-MB levels. The positives of these two indexes were observed in children with acute viral myocarditis rate. Results The positive rates of cTnT and CK-MB in pediatric patients with acute viral myocarditis were 94.3% and 95.5%, respectively. There was no significant difference between the two groups (P> 0.05). The specificity of cTnT for detecting acute viral myocarditis (92.2%) was superior to CK-MB (71.4%) and its sensitivity (94.3%) was lower than for CK-MB (95.5%). Conclusion cTnT detection is convenient, rapid and specific in the diagnosis of acute viral myocarditis in children. It has a good value for the diagnosis of acute viral myocarditis in children. Combined detection of cTnT and CK-MB can increase the diagnostic rate and reduce the rate of misdiagnosis .