论文部分内容阅读
目的了解福建省在无脊髓灰质炎后,病毒分离阳性的AFP病例流行特征。方法对2000—2012年病毒分离阳性的AFP病例进行流行病学分析。结果 13年共报告AFP病例1 822例,年均发病率1.70/10万。共采集1 807例标本进行病毒分离,PV阳性4.6%,NPEV阳性11.1%,PV+NPEV混合阳性0.4%,阴性83.9%。PV组中,<1岁占44.6%,流动人口占10.8%,未全程免疫占24.1%,残留麻痹率27.7%,均高于其他组;NPEV组中,<1岁仅占9.5%,流动人口仅占2.5%,未全程免疫仅占9.0%,残留麻痹率仅12.4%。结论在维持无脊灰阶段,需继续提高口服脊灰疫苗(OPV)覆盖率,重点是流动儿童和边远山区儿童。加强NPEV防控亦可减少AFP病例及致残率。
Objective To understand the epidemiological characteristics of AFP cases with positive virus isolation in Fujian Province without poliomyelitis. Methods The epidemiological analysis of AFP cases positive for virus isolation from 2000 to 2012 was conducted. Results A total of 1 822 AFP cases were reported in 13 years, with an average annual incidence of 1.70 / 100 000. A total of 1 807 samples were collected for virus isolation. PV positive was 4.6%, positive NPEV was 11.1%, PV + NPEV mixed positive 0.4% and negative 83.9%. PV group, <1 year old accounted for 44.6%, floating population accounted for 10.8%, incomplete immunization accounted for 24.1%, residual paralysis rate 27.7%, were higher than other groups; NPEV group, <1 year old accounted for only 9.5% of floating population Only 2.5%, not full immunization only 9.0%, residual paralysis rate was only 12.4%. CONCLUSIONS: Oral poliovirus (OPV) coverage needs to continue to be elevated during the maintenance of poliomyelitis with a focus on migrant children and remote mountain children. Strengthening the prevention and control of NPEV can also reduce AFP cases and disability rates.