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目的 探讨胃镜下金属钛夹治疗非静脉曲张性上消化道出血的临床疗效.方法 将140例非静脉曲张性上消化道出血患者按照随机数字表法分为实验组与对照组,各70例.实验组给予金属钛夹治疗,对照组给予注射肾上腺素治疗,比较两组患者的止血情况、临床疗效、症状改善时间及并发症情况.结果 治疗后实验组止血率显著高于对照组(P＜0.05或0.01),治疗总有效率显著高于对照组(P＜0.05),再出血率显著低于对照组(P＜0.05),症状改善时间及住院时间均显著短于对照组(P＜0.01),两组均未发生并发症.结论 胃镜下金属钛夹治疗非静脉曲张性上消化道出血安全有效,止血率高,再出血率低,但必须严格把握手术适应证与禁忌证.“,”Objective To investigate the clinical effect of endoscopic metal titanic clip in the treatment of non variceal upper gastrointestinal bleeding. Method 140 cases of patients with nonvariceal upper gastro-intestinal bleeding were divided into the experimental group and the control group according to the random number table method,70 cases in group. The experimental group was given the treatment of metal titanic clip,the control group was given the injection of epinephrine treatment. The hemostasis condition,clinical curative effect, symptom improvement time and complication condition of the two groups were compared. Results After treatment,the hemostasis rate at each time point in the experimental group was higher than that in control group (P＜0.05 or 0.01); the total effective rate of the experimental group was higher than that of control group (P＜0.05),the rebleeding rate was lower than that of the control group (P＜0.05),the symptom improvement time and hospitalization time in the experimental group were significantly shorter than those in the control group (P ＜0.01), and there were no complications in the two groups. Conclusion Endoscopic metal titanic clip in the treatment of non variceal upper gastrointestinal bleeding is safe and effective, with high hemostasis rate,low rebleeding rate, and the operative indications and contraindication should be strictly controlled.