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目的分析珠池医院2010～2012年疑似预防接种反应(AEFI)发生特征,了解预防接种安全性,为提高预防接种质量提供依据。方法采用描述性流行病学方法对收集的AEFI数据进行分析。结果珠池医院2010～2012年共报告AEFI为273例,发生率为70.47/10万,3年分别为132例(110.20/10万),67例(55.24/10万),74例(50.58/10万),一般反应有246例占90.11%,偶合反应24例,占8.79%,异常反应3例,占1.10%,无疫苗质量事故、接种事故;一类疫苗发生AEFI为205例,发生率为71.52/10万,以百白破、白破二联、含麻疹类疫苗、A群流脑疫苗、乙脑疫苗为主,二类疫苗发生AEFI为68例,发生率为67.51/10万,以甲型流感(裂解)疫苗、流感疫苗、口服轮状病毒疫苗、水痘疫苗、狂犬疫苗、23价肺炎疫苗为主。2010年、2011年一类疫苗之间、二类疫苗之间AEFI发生率差别均有显著性。结论认真做好接种前告知、接种规范培训、接种后观察工作,同时开展AEFI诊断、处理、调查培训,可以有效减少AEFI和接种事故的发生,同时能提高AEFI监测的准确性。
Objective To analyze the characteristics of suspected immunization response (AEFI) in Zhuchi Hospital from 2010 to 2012, and to understand the safety of vaccination and provide the basis for improving vaccination quality. Methods The collected AEFI data were analyzed using a descriptive epidemiological approach. Results A total of 273 AEFI cases were reported in Zhuchi Hospital from 2010 to 2012, with a prevalence of 70.47 / 100 000, 132 cases (110.20 / 100000), 67 cases (55.24 / 100000), 74 cases (50.58 / There were 246 cases (90.11%) in general reaction, 24 cases (8.79%) in coupling reaction, 3 cases (1.10%) in abnormal reaction, no vaccine accident and vaccination accident. The incidence of AEFI in one kind of vaccine was 205 Was 71.52 / 100000, with diphtheria breach, white broken two together, including measles vaccine, A group meningitis vaccine, Japanese encephalitis vaccine, two types of vaccine AEFI occurred in 68 cases, the incidence was 67.51 / 100000, Influenza type A (lytic) vaccine, influenza vaccine, oral rotavirus vaccine, varicella vaccine, rabies vaccine, 23-valent pneumovirus mainly. The difference in the incidence of AEFI between 2010 and 2011 vaccines and between the two vaccines was significant. Conclusions Earnest pre-vaccination training, standardized vaccination training and post-vaccination observation, as well as AEFI diagnosis, treatment and investigation training, can effectively reduce the incidence of AEFI and vaccination accidents and improve the accuracy of AEFI monitoring.