多发性内分泌腺机能减退综合征,又称自身免疫多内分泌病综合征,国内报道甚少。我院近年来收治2例,报道如下: 例1女,54岁。10年前畏寒、乏力、浮肿、食欲减退,在外院查BMR-19.5%,甲状腺吸碘功能降低,诊断为甲减。用甲状腺片治疗后症状收善。因停药后症状复发而常年间断服用甲状腺片。入院前一月余出现多饮、多尿、多食,体重减轻十余斤;入院四个月前测空腹血糖87mg%。无结核、肝病及糖尿病家族史。足月顺产7胎,月经正常,51岁闭经。体检:血压110/68,体重51.5kg,颜面轻浮,眉毛稀少,头发脆干易脱落。甲状腺不大,心肺(-),心率82,律齐。肝肋下1cm,脾未及。实验室检查:血 Multiple endocrine hypogonadism syndrome, also known as autoimmune polyendocrinopathy syndrome, rarely reported. In recent years, our hospital admitted in 2 cases, reported as follows: A female, 54 years old. 10 years ago chills, weakness, edema, loss of appetite, check the BMR-19.5% in the outer court, thyroid iodine reduced function, diagnosis of hypothyroidism. Thyroid tablets treated with symptoms improved. Due to the recurrence of symptoms after discontinuation of perennial thyroid tablets. More than a month before admission appeared to drink more, more urine, more food, weight loss of more than ten pounds; four months before admission measured fasting blood glucose 87mg%. No tuberculosis, liver disease and family history of diabetes. Full-term 7-fetus, normal menstruation, 51-year-old amenorrhea. Physical examination: blood pressure 110/68, weight 51.5kg, facial frivolous, scarce eyebrows, hair brittle dry easy to fall off. Small thyroid, cardiopulmonary (-), heart rate 82, law Qi. Liver ribs 1cm, spleen and time. Laboratory tests: blood