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目的探讨美蓝行前哨淋巴结(SLN)活检在基层医院早期低危乳腺癌手术中的应用。方法对32例入选乳腺癌患者行美蓝染色法检测SLN,并对其中5例SLN阳性者行腋窝淋巴结清扫术(ALND)。结果 32例中31例检出SLN,检出率为96.9%,共检出SLN40个,其中1个者17例,2个者10例,3个者3例,4个者1例。对术中病理切片检查结果提示SLN阳性患者5例行ALND;其余SLN阴性的27例患者则避免了ALND。结论应用美蓝行SLN活检是一种简单、经济而且有效的方法。对于早期乳腺癌常规行SLNB,可使早期低危乳腺癌患者发生与腋窝淋巴结清除术相关并发症的危险降低。
Objective To investigate the application of the methylene blue sentinel lymph node (SLN) biopsy in the early stage of low-risk breast cancer surgery in primary hospitals. Methods SLN was detected by methylene blue staining in 32 patients with breast cancer, and axillary lymph node dissection (ALND) was performed in 5 SLN patients. Results Among the 32 cases, SLN was detected in 31 cases and the detection rate was 96.9%. There were 40 SLNs detected, of which 1 was in 17 cases, 2 were in 10 cases, 3 were in 3 cases and 4 were in 1 case. The intraoperative biopsy results suggested that ALND was absent in 5 of 5 SLN-positive patients and ALND was avoided in the remaining 27 patients with SLN-negative. Conclusion The application of methylene blue SLN biopsy is a simple, economical and effective method. The routine use of SLNB for early breast cancer reduces the risk of complications associated with axillary lymph node dissection in patients with early-stage low-risk breast cancer.