【病例】　女,57y。因冠心病、心绞痛于1999年3月23日入院。既往有类风湿关节炎病史,无药物过敏史,家族中无血液病史。查体:生命体征无异常,一般情况好,双手指呈梭状畸形,右膝关节活动受限。血常规:血小板141×109/L,血沉67mm/h,类风湿因子(+),C反应蛋白(+),肝功能正常。入院后 [Case] ​​Female, 57y. Due to coronary heart disease, angina was admitted on March 23, 1999. Past history of rheumatoid arthritis, no drug allergy history, family history of no blood disease. Physical examination: no abnormal vital signs, the general situation is good, his fingers were fusiform deformity, right knee joint activity is limited. Blood: platelets 141 × 109 / L, erythrocyte sedimentation rate 67mm / h, rheumatoid factor (+), C reactive protein (+), normal liver function. After admission