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沙眼衣原体(Chlamydia trachomatis,CT)是一种严格细胞内寄生、有独特发育周期的原核细胞型微生物。CT在宿主细胞浆内增殖,形成光镜可见的典型细胞内包涵体,包涵体为CT在宿主细胞内的生长繁殖提供屏障保护,同时也是CT与宿主细胞进行物质交换和信息传递的门户,CT不仅可从宿主细胞摄取营养物质,还可分泌效应蛋白进入宿主细胞质调节宿主细胞功能。CT基因组DNA序列和功能注释完成后,衣原体蛋白的亚细胞定位、
Chlamydia trachomatis (CT) is a kind of prokaryote-type microorganism with strict intracellular parasitism and unique developmental cycle. CT proliferates in the host cytoplasm to form typical intracellular inclusions visible in light microscopy. Inclusion bodies provide barrier protection for the growth and reproduction of CT in host cells, and are also the gateway for substance exchange and information transfer between CT and host cells. CT Not only nutrients can be taken from the host cells, but also secreted the effector protein into the host cytoplasm to regulate host cell function. Subsequent to the completion of the CT genomic DNA sequence and functional annotation, the subcellular localization of the Chlamydia protein,