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根据流行病学的观察,作者推测客观存在着一种通过粪—口途径传布的非甲非乙型肝炎病毒。为证实这一点,作者选择9例疑为粪—口传染的非甲非乙型肝炎病人,在黄疸出现后1～4天收集其粪便并制成10%提取液,经混合、离心、除菌过滤,最后浓缩100倍。将浓缩的粪滤液给志愿者口服。该志愿者在试验前抗HA阳性,但HBsAg,抗HBs均阴性。口服后从第10天起不定期的采集粪便及血清标本。结果在口服试验后36天,志愿者发生典型的急性肝炎症状,伴有
According to epidemiological observations, the authors speculate that there is an objective existence of a non-A, non-B hepatitis virus transmitted through the fecal-oral route. To confirm this, we selected 9 cases of non-A, non-A, non-B hepatitis patients suspected of faecal-oral infection to collect their stool 1 to 4 days after the onset of jaundice and made 10% extract. After mixing, centrifugation and sterilization Filtration, the final concentration of 100 times. The concentrated fecal filtrate was given orally to volunteers. The volunteers anti-HA positive before the test, but HBsAg, anti-HBs were negative. From the 10th day after oral administration, fecal samples and serum samples were collected irregularly. Results 36 days after oral administration, volunteers developed typical acute hepatitis symptoms associated with them