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26例青少年型日本血吸虫病性侏儒症患者,计男性9例、女性17例,年龄12-20岁。随机分为3组,並给于不同方法治疗:一组(9例)LRH-A12.5μg一次静脉注射;二组:(7例)LRH-A12.5μg一次静脉注射后一年,再给于LRH—A5μg,肌注,每周2次共8周;另加TRH1mg,鼻内喷雾给药,每日一次共18周;三组:(10例)LRH-A5μg,肌注,每周2次,共8周,另加TRH1mg,鼻内喷雾给药,每日一次共2个月。以观察各治疗方法对该类患者生长发育情况和血激素水平的影响。结果发现:上述各治疗方法对患者的生长发育和激素水平的改善均有明显的促进作用,並以2组为优。因此,我们认为单用LRH-A或LRH-A与TRH合用,对青少年型日本血吸虫病性侏儒症患者的生长发育是有帮助的,值得临床进一步研究使用。
26 cases of juvenile schistosomiasis japonica dwarfism patients, including 9 males and 17 females, aged 12-20 years. A randomized divided into 3 groups, and given different treatment: a group (9 cases) of LRH-A12.5μg a intravenous injection; two groups: (7 cases) LRH-A12.5μg a intravenous injection one year, LRH-A5μg, intramuscular injection, twice a week for 8 weeks; plus TRH1mg, nasal spray administered once daily for 18 weeks; three groups: (10 cases) LRH-A5μg, intramuscular injection twice a week , A total of 8 weeks, plus TRH1mg, nasal spray, once daily for 2 months. To observe the treatment of these patients growth and development and blood hormone levels. The results showed that: The above treatment of patients with growth and hormone levels were significantly improved, and two groups as the best. Therefore, we believe that the combined use of LRH-A or LRH-A alone with TRH is helpful for the growth and development of juvenile schistosomiasis japonica, which is worthy of further clinical study.