1-芳基取代吡咯中有许多具有明显的生理效应.我们曾以1-对氯苯基-3-乙酰基-1,4-戊二酮,1,4-二苯基-2-苯甲酰基-1,4-丁二酮,与各种芳香族伯胺在冰醋酸催化下环合制得了相应的1-芳香多取代吡咯.但用冰醋酸作催化剂时,产品的分离精制常会遇到困难.我们按文献[3]合成的固体超酸二氧化锆用于催化酯化反应,效果良好.本文进一步在固体超酸二氧化锆的催化下将1-间硝基苯基-3-乙酰基-1,4-戊二酮 Many of the 1-aryl-substituted pyrroles have significant physiological effects.We have used 1-p-chlorophenyl-3-acetyl-1,4-pentanedione, 1,4-diphenyl- Acyl-1,4-butanedione, cyclization with various aromatic primary amines under the catalysis of glacial acetic acid gave the corresponding 1-aromatic substituted pyrroles, but when using glacial acetic acid as the catalyst, the separation and purification of the products often encountered Difficult.We synthesized according to the literature [3] solid super acid zirconium dioxide for the esterification reaction with good results.In this paper, the solid super acid zirconium dioxide catalyst 1-m-nitrophenyl-3-acetyl Yl-1,4-pentanedione