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采用ＥＬＩＳＡ双抗体夹心法对８６例急性脑血管病（ＡＣＶＤ）患者及４２例正常对照血清可溶性白细胞介素２受体（ｓＩＬ－２Ｒ）水平进行了动态检测。结果显示脑梗塞和脑出血急性期血清ｓＩＬ－２Ｒ水平明显高于对照组；血清ｓＩＬ－２Ｒ水平变化既与出血量、梗塞体积密切相关，也与ＡＣＶＤ预后密切相关；动态观察显示恢复期患者血清ｓＩＬ－２Ｒ水平显著低于急性期患者，但仍然明显高于正常对照组。结果提示急性期及恢复期的ＡＣＶＤ患者Ｔ细胞处于活化状态，检测ｓＩＬ－２Ｒ对判断ＡＣＶＤ病情、推测预后有重要临床价值
Serum levels of soluble interleukin 2 receptor (sIL-2R) in 86 patients with acute cerebrovascular disease (ACVD) and 42 normal controls were detected by ELISA double antibody sandwich method. The results showed that serum sIL-2R levels in acute stage of cerebral infarction and cerebral hemorrhage were significantly higher than those in control group. Serum sIL-2R levels were closely related to both hemorrhage volume and infarct volume, but also to ACVD prognosis. Dynamic observation showed that serum levels of sIL- sIL-2R levels were significantly lower than those in acute phase, but still significantly higher than the normal control group. The results suggest that acute and convalescent ACVD T cells in patients with activation, the detection of sIL-2R ACVD judgment of the disease, the prognosis of the prognosis of important clinical value