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1850年maclntyre首先在尸体解剖中发现骨髓瘤,当时由于患骨希疏而脆,定名为“骨软化松脆症”,至1973年Rustizky对该病病理作了明确的描述后,才正式迠议定名为骨髓瘤。①骨髓瘤是骨髓造血系统的恶性肿瘤,来沅于骨髓的成桨细胞者最多,故称为桨细胞骨髓瘤,(Plasma—cell myeloma)。其特点是桨细胞或者异常旦白质的浸润。国外这种肿瘤系骨恶性肿瘤中最常见的。Dahlin 1957年2276例骨恶性肿瘤中就有563例(34％),占骨恶性肿瘤的第一位。国内文献始于1917年就有报导。迄今约80例。但尚未单独见到侵犯颌骨的报导。我科1960年至今收治四例首先发现于颌骨的桨细胞骨髓瘤,均经病理检查确诊。特作介绍,并简单复习文献。
1850 maclntyre first found in autopsy myeloma, at that time due to the bones and sparse and crisp, named as “osteomalacia crispus disease” until Rustizky in 1973 made a clear description of the pathology of the disease before formally agreed Named myeloma. ① myeloma is a malignant tumor of the hematopoietic system of the bone marrow, Yuan Yuan in the bone marrow into the most paddle cells, it is called the paddle cell myeloma, (Plasma-cell myeloma). It is characterized by paddle cells or abnormal infiltration of denatured protein. Foreign such tumors are the most common malignant bone tumors. Dahlin In 1957 2276 cases of bone malignancies, there are 563 cases (34%), the first of malignant tumors. Domestic literature began to be reported in 1917. So far about 80 cases. However, the jaw violation has not been seen separately. Four cases of myeloid myeloma first found in the jaw bone were treated in our department from 1960 to the present and were confirmed by pathological examination. Special presentation, and a brief review of the literature.