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1989年3月至1992年3月,收治首程根治性放疗鼻咽癌389例,其中1期5例,Ⅱ期22例,Ⅲ期201例,Ⅳ期161例。Ⅲ~Ⅳ期占93.1％。全部采用~60Co外照射。总剂量DT68GY~DT72GY。总剂量中一半以面颈联合野照射,其余面颈分野照射。结果：全部病人随访5年以上,随访率91.5％;全组5年生存率48.1％;I~Ⅳ期5年生存率分别为80％、81.8％、57.2％、30.4％;5年内鼻咽／颈结复发率17.7％,复发病例88.3％在放疗后3年内;死亡202例中,明确死因为164例,其中64％死于远处转移,死于复发占22％。结论：T／N分期愈晚,预后愈差。失败原因主要为远处转移及复发。早期发现和治疗病人是提高鼻咽癌治愈率的关键。
From March 1989 to March 1992, 389 cases of nasopharyngeal carcinoma were treated with radical radiotherapy, including 5 cases of stage 1, 22 cases of stage Ⅱ, 201 cases of stage Ⅲ and 161 cases of stage Ⅳ. Ⅲ ~ Ⅳ accounted for 93.1%. All use ~ 60Co external irradiation. Total dose DT68GY ~ DT72GY. Half of the total dose of facial and neck joint field irradiation, the other surface neck irradiation. Results: All patients were followed up for more than 5 years with a follow-up rate of 91.5%; the 5-year overall survival rate was 48.1%; the 5-year survival rates of stage I-IV were 80%, 81.8%, 57.2% and 30.4% Neck recurrence rate of 17.7%, 88.3% of cases of recurrence within 3 years after radiotherapy; death of 202 cases, the clear cause of death was 164 cases, of which 64% died of distant metastasis, died of recurrence accounted for 22%. Conclusion: The later the T / N stage, the worse the prognosis. The main reasons for the failure of distant metastasis and recurrence. Early detection and treatment of patients is to improve the cure rate of nasopharyngeal cancer key.