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患者,女,32岁,被诊断为纵隔未分化大细胞非霍奇金淋巴瘤,化疗后3a出现双眼悬浮物和右眼视力下降。眼科检查发现带有多发深在的左眼脉络膜病变的双侧全葡萄膜炎。眼窝电脑断层扫描显示两侧球后视神经部分加强和大块的视神经鞘。该患者接受眼窝受累区域放射治疗,累积剂量为30戈瑞。放射治疗8mo后,发展为黄斑部视网膜色素上皮脱离和右侧颞上和鼻下区眼底的深脉络膜视网膜变性。在脉络膜视网膜变性区边缘有玻璃体视网膜牵引迹象,从而路障激光在受累眼睛进行。双眼视力仍然6/6。视网膜色素上皮脱离可能是放射治疗非霍奇金淋巴瘤眼内转移时的并发症。至关重要的是提醒了眼科医生这个罕见的并发症。
The patient, female, 32 years old, was diagnosed as mediastinal undifferentiated macrophages in non-Hodgkin’s lymphoma. Susceptibility of both eyes to suspended matter and right eye decreased after 3a. Ophthalmologic examination revealed bilateral uveitis with multiple deep left choroidal lesions. The orbital computed tomography showed partial enhancement of the posterior optic nerve and the massive optic nerve sheath on both sides of the ball. The patient underwent radiotherapy in the affected eye area with a cumulative dose of 30 Gy. After 8 months of radiotherapy, macular retinal pigment epithelium detachment and deep chorioretinal degeneration in the right superior temporal and superior fundus were developed. There are signs of vitreoretinal traction at the edge of the choroid retinal degeneration area, and the roadblock laser is carried out in the affected eye. Binocular vision is still 6/6. Retinal pigmented epithelial detachment may be a complication of radiation therapy for non-Hodgkin’s lymphoma intraocular metastasis. It is crucial to remind the ophthalmologist of this rare complication.