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目的:研究糖尿病筛查和诊断中糖化血红蛋白(HbAlc)检验的应用及价值。方法:选取2015年1月-2015年12月本院收治的982例糖尿病患者作为观察组,选取同期进行健康体检的750例正常人作为对照组,分别对两组受试者的HbAlc及其他血糖指标进行检测,比较两组检测结果的差异性。结果:观察组空腹血糖为(8.58±3.28)mmol/L,餐后2 h血糖为(11.59±3.96)mmol/L,HbAlc为(8.76±2.30)%;对照组空腹血糖为(4.22±1.58)mmol/L,餐后2 h血糖为(7.62±3.47)mmol/L,HbAlc为(3.86±1.03)%,两组比较,差异具有统计学意义(P<0.05);根据HbAlc 8%的临界划分标准,将观察组患者分为HbAlc≤8%组和HbAlc>8%两组,组间比较,HbAlc>8%组的并发症及合并症发生率明显高于HbAlc≤8%组,差异具有统计学意义(P<0.05)。结论:糖尿病筛查和诊断中检测HbAlc,有利于准确诊断糖尿病,并对糖尿病早期及糖尿病并发症做好防控措施。
Objective: To study the value and application of HbAlc in screening and diagnosis of diabetes mellitus. Methods: One hundred and eighty-two diabetic patients admitted from January 2015 to December 2015 in our hospital were selected as the observation group. 750 normal subjects were selected as control group during the same period. HbA1c and other blood glucose Indicators were tested to compare the differences between the two test results. Results: The fasting blood glucose in the observation group was (8.58 ± 3.28) mmol / L, the postprandial blood glucose was 11.59 ± 3.96 mmol / L and the HbAlc was (8.76 ± 2.30)% in the observation group. The fasting blood glucose in the control group was (4.22 ± 1.58) (7.62 ± 3.47) mmol / L and HbA1c (3.86 ± 1.03)% at 2 h postprandial, the difference was statistically significant (P <0.05). According to the critical classification of HbAlc at 8% Standard, the observation group was divided into HbAlc≤8% group and HbAlc> 8% two groups, the comparisons between groups, HbAlc> 8% group was significantly higher than the incidence of complications and HbAlc≤8% group, with statistical differences Significance (P <0.05). Conclusion: The detection of HbA1c in the screening and diagnosis of diabetes is helpful for the accurate diagnosis of diabetes mellitus, and the prevention and control of diabetes mellitus and complications in the early stage of diabetes.