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近来,血清催乳素(PRL)测定已成为检查闭经患者不可缺少的步骤之一。据报告,20%的闭经患者有高PRL血症。作者发现50%的高PRL血症者在一生中的某段时期接受过口服避孕药(OC)。动物实验已证实避孕丸与高PRL血症有关。Reyniak等发现接受OC的患者30%有高PRL血症。过去十年中,分泌PRL的垂体肿瘤发病率增加,Sherman等认为这与OC的使用有关。但Annegers等认为垂体肿瘤发病率增加是由于有了更好的诊断技术。本文作者研
Recently, the serum prolactin (PRL) assay has become an indispensable step in examining amenorrhea patients. It is reported that 20% of amenorrhea patients have high PRL hyperlipidemia. The authors found that 50% of people with high PRL dis- ease had received oral contraceptives (OC) for some time of their life. Animal experiments have confirmed that contraceptive pills and high PRL hyperlipidemia. Reyniak et al found that 30% of patients who underwent OC had high PRL. The incidence of pituitary tumors that secrete PRL has increased over the past decade, and Sherman et al. Conclude that this is related to the use of OC. However, Annegers et al. Argue that the increased incidence of pituitary tumors is due to better diagnostic techniques. The author of this research