读谢汝能等同志的《实验性锡尘沉着症的初步观察》一文后,觉得有些问题需要商榷,提出供讨论。 1.关于锡尘有无致纤维化作用的问题。该文在三处涉及此事:在实验结果项中记载,氧化锡组及凝灰组之粉尘灶中,均可见到少量的成纤维细胞及网状纤维增生,在讨论项中也提出“锡尘在肺中并未发现有明显致纤维性变”,并指出锡尘组的结节“长久保持在Ⅰ—Ⅱ级之间,绝无融合现象”,而同期的石英组已发展为Ⅳ级,且有显著融合”;进而在小结中提出“氧化锡只产生一种沉着作用,或有极轻微细胞反应,但不导致纤维性变”。综上可知,作者们对锡尘的致纤维化作用是持否定 Reading Xie Runeng comrades, such as “experimental observation of tin dust deposition,” a text, I feel that some issues need to be discussed, put forward for discussion. 1 on the tin dust caused by the problem of fibrosis. This article deals with the matter in three places: In the experimental results, there are few fibroblasts and reticular fibrosis seen in the dust pots of the tin oxide group and the tuff group. In the discussion item, “tin Dust in the lungs did not find significant cause fibrosis ”, and pointed out that tin dust group nodules“ long-term maintained in the Ⅰ-Ⅱ level between no fusion ”and the same period of the quartz group has developed into Ⅳ , And there is a significant fusion. “Further in the summary,” tin oxide only produces a sedative effect, or very slight cell reaction, but does not lead to fibrous changes. "To sum up, we know that the cause of tin dust fibrosis The role is negative