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目的总结在老年晚期胃癌手术中联合应用铜绿假单胞菌注射液(万特普安)后的短期临床疗效观察。方法纳入老年晚期胃癌行姑息手术治疗并在术中应用铜绿假单胞菌注射液治疗组25例,仅行姑息性手术的对照组25例。手术后给予相同治疗措施,出院后予以定期门诊随诊,复查相关检查,了解治疗结束后的死亡原因和时间,统计分析1年生存率及中位生存期。结果在短期临床疗效观察中,治疗组中位生存期为11.5个月,对照组中位生存期为8.0个月,治疗组生存率稍高于对照组,表现出治疗有效的态势。结论术中应用铜绿假单胞菌注射液能对提高老年晚期胃癌患者的生存期有一定的帮助,而可否长期生存还需继续观察。
Objective To summarize the short-term clinical efficacy of combined use of Pseudomonas aeruginosa injection (Vantaaan) in elderly patients with advanced gastric cancer. Methods Twenty-five elderly patients with gastric cancer undergoing palliative surgery and 25 patients with Pseudomonas aeruginosa injection were enrolled in this study. Twenty-five patients underwent palliative surgery. After the operation, the same treatment measures were given. After leaving the hospital, regular outpatient follow-up and follow-up examination were carried out to understand the cause and time of death after the end of treatment. The 1-year survival rate and median survival time were statistically analyzed. Results In the short-term clinical observation, the median survival time was 11.5 months in the treatment group and 8.0 months in the control group. The survival rate of the treatment group was slightly higher than that of the control group, showing a therapeutic effect. Conclusion Intraoperative use of Pseudomonas aeruginosa injection can improve the survival of patients with advanced gastric cancer in some help, but the long-term survival needs to be observed.