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目的：研究胃癌细胞淋巴道转移机理。方法：用图像分析仪测定３２例胃癌组织及癌旁组织内有腔淋巴管和毛细淋巴管最大面积、周径和管径。结果：在胃癌组织内以条索状毛细淋巴管为多，而在癌旁组织内则以开放的淋巴管和毛细淋巴管为主；图像分析结果表明：转移组胃癌组织与癌旁组织内淋巴管和毛细淋巴管腔面积、周径和管径，两者间彼此差异均有显著性（Ｐ＜０．０５）；未转移组胃癌组织与癌旁组织内淋巴管和毛细淋巴管腔面积、周径和管径两者间差异亦有显著性（Ｐ＜０．０５）；比较转移组与未转移组癌旁组织内淋巴管毛细淋巴管最大腔面积、周径和管径，彼此差异亦有显著性（Ｐ＜０．０５）。结论：结果提示胃癌旁组织间质水肿导致淋巴管和毛细淋巴管扩张，有助于癌细胞的转移，癌细胞转移是通过浸润癌成熟的毛细淋巴管转移到淋巴结的。
Objective: To study the mechanism of lymphatic metastasis of gastric cancer cells. Methods: The maximum area, diameter and diameter of lymphatic vessels and lymphatic capillaries in 32 cases of gastric cancer and adjacent tissues were measured by image analyzer. RESULTS: There were more cordial lymphatic vessels in the gastric cancer tissues, and there were mainly open lymphatic vessels and lymphatic capillaries in the adjacent tissues. Image analysis showed that the metastatic group had gastric lymphoid tissue and adjacent lymph tissues. The lymphatic lumen area, peripheral diameter and caliber of the tube and capillary lymph node were significantly different from each other (P<0.05). The lymphatic and capillary lymphatic lumen area in the non-metastasis group was similar to that in the adjacent tissue. There was also a significant difference between the circumference and the diameter (P<0.05); the maximum luminal area, peripheral diameter, and diameter of the lymphatic capillaries in the lymph nodes adjacent to the metastatic and non-metastatic tissue were also different. Significant (P < 0.05). Conclusions: The results suggest that the interstitial edema around gastric cancer leads to the expansion of lymphatic vessels and lymphatic capillaries, which contributes to the metastasis of cancer cells. Metastasis of cancer cells occurs through the infiltration of mature lymphatic capillaries into the lymph nodes.