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白血病皮肤损害并不少见,但国内报道较少。我院自1979年～1988年收治白血病176例,其中有皮肤损害8例(4.5％),现分析如下:1一般资料皮肤损害8例中,男6例、女2例,年龄21～51岁,慢性粒细胞白血病(慢粒)4例(2例急性变);急性非淋巴细胞白血病(急非淋)2例(均为M_2型)。急性淋巴细胞白血病(急淋)1例(L_1型),慢性淋巴细胞白血病(慢淋)1例。其诊断依据:①白血病诊治过程中发生皮肤损害。②化疗后皮损消失。③局部皮肤活检有白血病细胞浸润。8例中5例经皮肤活检证实,3例化疗后皮损消失。
Leukemia is not uncommon skin damage, but fewer domestic reports. Our hospital from 1979 to 1988, 176 cases of leukemia, of which 8 cases of skin lesions (4.5%), are as follows: 1 General Information 8 cases of skin lesions, 6 males and 2 females, aged 21 to 51 years , 4 cases of chronic myelogenous leukemia (CML) (2 cases of acute change), 2 cases of acute non-lymphocytic leukemia (JFD) (all M_2). 1 cases of acute lymphoblastic leukemia (acute lymphoblastic), 1 cases of chronic lymphocytic leukemia (chronic lymphocytic leukemia). The diagnosis is based on: ① leukemia in the diagnosis and treatment of skin lesions. The skin lesions disappear after chemotherapy. ③ local skin biopsy leukemia cell infiltration. Five of the eight cases were confirmed by skin biopsy and the lesions disappeared after three cases of chemotherapy.