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目的 :探讨肺动脉高压患者左室功能变化及其可能的机制。方法 :采用超声心动图测定 2 4例慢性血栓栓塞性肺动脉高压和 8例原发性肺动脉高压患者的左室收缩和舒张功能。结果 :两种肺动脉高压患者 ,其左室射血分数在正常范围 ,二尖瓣E峰流速降低 ,舒张早期快速充盈减速时间 (EDT)延长 ,E/A <1,心室等容舒张时间间期 (IVRT )明显延长 ,表现为舒张功能指标变化为主。
Objective: To investigate the changes of left ventricular function in patients with pulmonary hypertension and its possible mechanism. Methods: Echocardiography was used to measure left ventricular systolic and diastolic function in 24 patients with chronic thromboembolic pulmonary hypertension and 8 patients with primary pulmonary hypertension. Results: The left ventricular ejection fraction (LVEF) was decreased in the normal range, the mitral E peak velocity was decreased, the early diastolic filling time (EDT) was prolonged in both PAH patients. E / A <1, (IVRT) was significantly prolonged, manifested as changes in diastolic function-based.