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该文是TIMI-10B研究的部分结果,目的是分析血清生化指标肌红蛋白(Mb)、肌酸磷酸激酶MB(CK-MB)和心肌钙蛋白I(cTnI)测定是否有助于判断急性心肌梗死病人溶栓治疗后梗死相关动脉(IRA)的通畅情况。三项指标都用荧光酶联免疫方法测定,以ng/ml为表达单位。溶栓用t-PA静脉注射。IRA的通畅程度根据溶栓后60分钟时的冠状动脉造影结果分析。共有422例的生化指标和造影结果可供分析,其中378例在胸痛开始后6小时内作溶栓治疗。
This article is part of the TIMI-10B study to determine if serum biochemical markers of myoglobin (Mb), creatine phosphokinase MB (CK-MB), and cardiac troponin I (cTnI) are useful in determining acute myocardial infarction Infarct related artery (IRA) patency after infarction patients thrombolytic therapy. Three indicators were measured by fluorescence enzyme-linked immunosorbent assay, expressed in ng / ml units. Thrombolytic t-PA intravenously. The patency of IRA was based on coronary angiography at 60 minutes after thrombolysis. A total of 422 biochemical indicators and imaging results for analysis, including 378 cases of thrombolytic therapy within 6 hours after the start of chest pain.