橄榄桥脑小脑萎缩(olivopontocerebellar atrophies,OPCA)是一种遗传性共济失调疾病。本病呈常染色体显性或隐性遗传,成年起病,多为散发病例。病理变化与家族性发病者相同,都累及下橄榄核、小脑脚、桥脑底和小脑。临床表现以躯干运动不协调,进而肢体性共济失调、植物神经功 Olivopontocerebellar atrophies (OPCA) is a hereditary ataxia disease. The disease was autosomal dominant or recessive, adult onset, mostly sporadic cases. Pathological changes and familial onset are the same, all involving the next olive, cerebellar peduncle, pons and cerebellum. Clinical manifestations of uncoordinated trunk movement, and thus limb ataxia, autonomic dysfunction