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目的评价参附注射液治疗慢性心力衰竭疗效及对血清高敏C反应蛋白、白介素-6水平的影响。方法选择136例慢性心力衰竭患者,随机分为观察组与对照组,每组各68例。给予所有患者西医常规抗心衰治疗,同时观察组实施参附注射液治疗,将两组疗效、血清炎症因子及心功能指标变化进行对比。结果观察组患者总疗效较对照组显著提高,组间存在统计学差异(P<0.05);两组患者治疗后IL-6、hs-CRP水平及LVEF、LVEDD、BNP指标与治疗前相比均显著改善,且观察组改善幅度优于对照组,组间存在统计学差异(P<0.05)。结论给予慢性心力衰竭患者参附注射液治疗,有助于减少炎症反应,改善患者心功能状态。
Objective To evaluate the curative effect of Shenfu injection on chronic heart failure and its effect on serum high sensitive C-reactive protein and interleukin-6 levels. Methods 136 patients with chronic heart failure were randomly divided into observation group and control group, 68 cases in each group. All patients were given conventional anti-heart failure treatment, while the observation group implemented Shenfu injection treatment, the two groups of curative effect, serum inflammatory factors and cardiac function changes were compared. Results The total curative effect of the observation group was significantly higher than that of the control group (P <0.05). The levels of IL-6, hs-CRP and the levels of LVEF, LVEDD and BNP Significantly improved, and the observation group improved better than the control group, there was a statistically significant difference (P <0.05). Conclusions The treatment of Shenfu injection in patients with chronic heart failure can reduce the inflammatory reaction and improve the cardiac function of patients.