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目的:评价瘤体内注射斯普林加放疗在治疗体表肿瘤中的作用。资料与方法:60例首次接受放疗的体表鳞癌被随机分两组。30例单纯放疗,30例在放疗中以8~10ml斯普林针瘤内注射,隔日1次。两组放疗方式剂量相同。每次17~2Gy,每周5次,总剂量60~70Gy。结果:单放组总有效率567%,综合组867%,有显著差别。放疗局部皮肤反应综合组明显轻于单放组。综合组治疗后的WBC、NK活性、T3、T4、T4/T8等值均优于单放组,差异有统计学意义。结论:在放疗中,联合在瘤体注射斯普林,能提高疗效,减轻局部放疗反应。同时有保护血象、增强免疫的作用
Objective: To evaluate the role of intratumoral injection of spring plus radiotherapy in the treatment of body surface tumors. Materials and Methods: Sixty cases of squamous cell carcinoma of the body undergoing radiotherapy for the first time were randomly divided into two groups. Thirty patients received radiotherapy alone and thirty patients received intratumoral injections of 8 to 10 ml of a spiraling needle during radiotherapy once a day. The two groups had the same dose of radiation therapy. Each time 1 7 ~ 2Gy, 5 times a week, the total dose of 60 ~ 70Gy. Results: The total efficiency of the radiotherapy group was 56.7%, and the comprehensive group was 86.7%. There was a significant difference. Radiotherapy local skin reactions in the comprehensive group was significantly lighter than the radiotherapy group. After treatment, WBC, NK activity, T3, T4, T4/T8 and other values of the comprehensive group were superior to those of the single-release group, and the difference was statistically significant. Conclusion: In radiotherapy, combined with the injection of spring in the tumor, can improve the efficacy and reduce the local radiotherapy response. At the same time protect blood and enhance immunity