本文对２８例原发性肝癌细胞超微结构进行观察（２６例肝细胞癌，１例混合型肝癌，１例胆管细胞癌）．发现肝癌细胞核明显增大，核外型极不规则，往往凹陷，多数核呈伪足状突起。大多数分化好的癌细胞质内出现较多的粗面内质网，常成层状排列；线粒体也较为丰富，并可见脂滴和少量的溶酶体。 In this paper, 28 cases of primary liver cancer cell ultrastructure were observed (26 cases of hepatocellular carcinoma, 1 case of mixed liver cancer, 1 case of cholangiocellular carcinoma). It was found that the nuclei of hepatocellular carcinoma cells were significantly enlarged, the nuclear appearance was extremely irregular, and they were often depressed, and most of the nuclei were pseudopodia. Most of the well-differentiated cancer cells showed more rough endoplasmic reticulum in the cytoplasm and often became lamellar; mitochondria were also abundant, and lipid droplets and a small amount of lysosomes were visible.