论文部分内容阅读
观察补肾通络疏肝方对衰老大鼠阴茎组织一氧化氮合成酶 (NOS)基因表达的影响。将衰老大鼠随机分为模型组、西地那非组、丙酸睾酮组、补肾通络疏肝方组与正常组 ( 2月龄大鼠 ) ,并应用PCR测定阴茎组织中NOSmRNA的表达 ,观察各组的变化。结果 :补肾通络疏肝方组阴茎组织中NOSmRNA的表达明显高于其他 4组 ,由多到少排定以下顺序 :西地那非组、正常组、丙酸睾酮组及模型组 ;补肾通络疏肝方组与西地那非组阴茎组织中NOSmRNA内控量较多 ,与其他各组比较有显著性差异 (P <0 .0 5)。结论 :补肾通络疏肝方有提高衰老大鼠阴茎组织中NOSmRNA表达的作用。
To observe the effect of Bushen Tonglu Shugan Decoction on the expression of nitric oxide synthase (NOS) gene in the penis of aging rats. The aged rats were randomly divided into model group, sildenafil group, testosterone propionate group, Bu Shen Tong Luo Shu Gan Fang group and normal group (2 month old rats), and the expression of NOS mRNA in the penis tissue was detected by PCR. Observe the changes in each group. Results: The expression of NOSmRNA in the penis tissue of Bushen Tongluo Shugan Recipe group was significantly higher than that of the other four groups. The following order was ordered: sildenafil group, normal group, testosterone propionate group and model group; Bushentong The amount of NOS mRNA in the penis tissue of the Luo Shugan Decoction group and the Sildenafil group was greater than that of the other groups (P < 0.05). Conclusion : Bushen Tongluo Shugan Recipe can increase the expression of NOSmRNA in the penis of aging rats.