原发性血小板增多症(ET),真性红细胞增多症(PV)均为少见病,而由ET转变为PV者更为少见,现报告一例。 患者:女,68岁,3年前起经常出现头晕、乏力、恶心等症状,但未曾就医。入院前一周出现牙龈出血,双下肢瘀斑及解黑便,于1987年4月19日收住院。查体:皮肤颜色正常,心肺无异常,肝脾均未扪及,双内踝见少量散在瘀斑。实验室检查:RBC2.75×1012/L,Hb80g/L,plt:(1680～2000)×10~9/L,WBC39×10~9/L,BT2min,CT4min,试管法凝血时间7min,PT19S,血块退缩试验6h及24h均部分退 Primary thrombocythemia (ET), polycythemia vera (PV) are rare, and from ET to PV were more rare, is a report. Patients: Female, 68 years old, often dizziness, fatigue, nausea and other symptoms since 3 years ago, but never sought medical treatment. One week before admission bleeding gums, both lower extremity ecchymosis and melena, was admitted to hospital on April 19, 1987. Physical examination: the skin color is normal, no abnormal heart and lung, liver and spleen are not palpable, double medial malleolus see a small amount of scattered ecchymosis. Laboratory tests: RBC2.75 × 1012 / L, Hb80g / L, plt: (1680 ~ 2000) × 10 ~ 9 / L, WBC39 × 10 ~ 9 / L, BT2min, CT4min, test tube clotting time 7min, PT19S, Clot regression test 6h and 24h are partially retreat