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目的:观察全膝关节置换术治疗膝关节骨性关节炎的效果。方法:选取浙江省荣军医院2017年4月至2019年4月收治的膝关节骨性关节炎患者80例为研究对象，采用随机数字表法分为对照组40例、观察组40例，对照组采用关节镜手术，观察组采用全膝关节置换术。比较两组术中出血量、切口愈合时间、住院时间、术后并发症发生率、膝关节活动度、疼痛视觉模拟(VAS)评分、美国特种外科医院(HSS)评分。结果:观察组术中出血量为(137.26±30.85)mL，少于对照组的(300.31±58.40)mL(n t＝15.613，n P<0.001)；观察组切口愈合时间、住院时间分别为(4.20±1.37)d、(7.58±1.20)d，均短于对照组的(6.89±2.43)d、(10.50±3.20)d，差异均有统计学意义(n t＝6.099、5.404，均n P<0.001)；观察组术后并发症发生率为7.50%(3/40)，低于对照组的25.00%(10/40)(χn 2＝4.501，n P<0.05)；观察组术后膝关节活动度为(106.71±15.38)°，大于对照组的(95.51±11.62)°(n t＝3.675，n P<0.001)；观察组术后VAS评分、HSS评分分别为(2.50±0.68)分、(89.27±5.65)分，均优于对照组的(4.53±0.71)分、(69.39±5.41)分，差异均有统计学意义(n t＝13.059、16.073，均n P<0.001)。n 结论:采用全膝关节置换术治疗膝关节骨性关节炎的效果显著，有助于患者术后膝关节功能的恢复。“,”Objective:To observe the effect of total knee arthroplasty in the treatment of knee osteoarthritis.Methods:From April 2017 to April 2019, 80 patients with knee osteoarthritis admitted to Zhejiang Rongjun Hospital were selected in the research.The patients were divided into control group(40 cases) and observation group(40 cases) according to the random digital table method.The control group was operated by arthroscopy, and the observation group was operated by total knee replacement.The bleeding volume, incision healing time, hospitalization time, incidence of postoperative complication, knee joint activity, VAS score and HSS score were compared between the two groups.Results:The amount of bleeding in the observation group was (137.26±30.85)mL, which was less than that in the control group[(300.31±58.40)mL](n t=15.613, n P<0.001). The healing time of incision and hospitalization time in the observation group were (4.20±1.37)d and (7.58±1.20)d, respectively, which were shorter than those in the control group[(6.89±2.43)d and (10.50±3.20)d], the differences was statistically significant(n t=6.099, 5.404, all n P<0.001). The incidence of postoperative complications in the observation group was 7.50%(3/40), which was lower than 25.00%(10/40) in the control group(χn 2=4.501, n P<0.05). The knee joint mobility of the observation group was (106.71±15.38)° after operation, which was higher than that of the control group[(95.51±11.62)°](n t=3.675, n P<0.001). The VAS score and HSS score of the observation group were (2.50±0.68)points and (89.27±5.65)points, which were better than those of the control group[(4.53±0.71)points and (69.39±5.41)points], the differences were statistically significant(n t=13.059, 16.073, all n P<0.001).n Conclusion:Total knee arthroplasty is effective in the treatment of knee osteoarthritis, which is helpful for the recovery of knee function.