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手足口病(HFMD)是人体感染肠道病毒造成口、手、足等身体部位出现疱疹性咽峡炎或皮疹、发热等为特征多见于小儿的急性肠道传染病。一般患者症状较轻微,少数患者可出现神经系统受损、呼吸道感染、无菌性脑炎等,部分重症者病情进展迅速、具有较高病死率。本研究对山东滨州市HFMD流行病学特征及病毒基因变异的生物学特征进行分析。1资料与方法1.1资料所有病例详细资料均来源于山东省疾病
Hand, foot and mouth disease (HFMD) is caused by the human body enterovirus causing mouth, hand, foot and other body parts appear herpes angina or rash, fever, etc. are more common in children with acute intestinal infectious diseases. In general, patients with mild symptoms, a small number of patients may appear nervous system damage, respiratory infections, aseptic encephalitis, etc., some severe cases of rapid progression, with a higher mortality. This study analyzed the epidemiological characteristics of HFMD and the biological characteristics of the viral genes in Binzhou, Shandong Province. 1 Materials and Methods 1.1 Information All the case details are derived from the disease in Shandong Province