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目的通过乌司他汀、生长抑素联合治疗重度急性胰腺炎的疗效观察,探讨有效的治疗方案。方法 86例重度急性胰腺炎患者作为研究对象,按照随机数字表法分为治疗组43例和对照组43例。对照组给予基础常规治疗,联合应用生长抑素;治疗组在对照组治疗基础上加用乌司他汀,观察两组的疗效,并进行分析比较。结果两组血尿淀粉酶及白细胞数恢复正常时间、腹痛腹胀消失时间、平均住院时间比较差异有统计学意义(P<0.05),治疗组总有效率93.0%优于对照组65.1%,差异有统计学意义(P<0.05)。结论乌司他汀联合生长抑素治疗重度急性胰腺炎的临床疗效显著,具有一定的临床意义。
Objective To investigate the curative effect of ulinastatin combined with somatostatin in the treatment of severe acute pancreatitis. Methods Totally 86 patients with severe acute pancreatitis were divided into treatment group (n = 43) and control group (n = 43) according to random number table. The control group received basic routine treatment and the combination of somatostatin. The treatment group was treated with ulinastatin on the basis of the control group. The curative effect of the two groups was observed and compared. Results There was significant difference between the two groups (P <0.05). The total effective rate was 93.0% in the treatment group and 65.1% in the control group, the difference was statistically significant Significance (P <0.05). Conclusion The clinical efficacy of ulinastatin and somatostatin in the treatment of severe acute pancreatitis is significant and has certain clinical significance.