纳洛酮联合脑苷肌肽注射液治疗急性重度酒精中毒的临床效果观察

来源 :临床合理用药杂志 | 被引量 : 0次 | 上传用户:hyc1211
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目的观察纳洛酮联合脑苷肌肽注射液治疗急性重度酒精中毒的临床疗效。方法选取医院收治的急性重度酒精中毒患者56例作为研究对象,随机分为观察组和对照组各28例。对照组采用纳洛酮治疗,观察组在对照组基础上联合脑苷肌肽注射液治疗,观察比较2组治疗后总有效率和苏醒时间、症状消失时间。结果经治疗,观察组总有效率为92.86%,高于对照组的78.57%(P<0.05);从苏醒时间和症状消失时间方面分析,观察组较对照组更优,差异有统计学意义(P<0.01)。结论纳洛酮联合脑苷肌肽注射液治疗急性重度酒精中毒效果显著,利于患者尽早脱离生命危险期,在临床上有推广和普及的价值。 Objective To observe the clinical efficacy of naloxone and encephalitoside in the treatment of acute severe alcoholism. Methods Fifty-six patients with acute severe alcohol poisoning admitted to hospital were selected as research object and randomly divided into observation group and control group with 28 cases each. The control group was treated with naloxone. The observation group was treated with encephalitoside combined with the control group. The total effective rate, recovery time and symptom disappearance time were observed and compared between the two groups. Results After treatment, the total effective rate in the observation group was 92.86%, which was higher than that in the control group (78.57%, P <0.05). From the aspects of recovery time and disappearance of symptoms, the observation group was better than the control group, the difference was statistically significant P <0.01). Conclusion Naloxone combined with encephalitoside in the treatment of acute severe alcoholism has a significant effect, which is beneficial to patients as soon as possible from the life-threatening stage and has clinical value of popularization and popularization.
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